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. 2021 Feb 19;10(2):233. doi: 10.3390/pathogens10020233

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Virucidal activity of OSCN⁻ and OSCN⁻/LF against SARS-CoV-2. SARS-CoV-2 was diluted in MEM and incubated for 1 h at 37 °C with only OSCN⁻ or supplemented with LF before infection of Vero-E6 cells. The reduction of infectivity was evaluated by plaque assay. (a) Virucidal effect of OSCN⁻; (b) comparison between different times of virus-OSCN⁻ exposure on the efficiency of the virucidal activity; (c) evaluation of the combination OSCN⁻+ LF on the virucidal activity. Data (mean ± SD, N = 3, experiments in duplicate) are percentages of no drug, set as 100%.