Scheme 9.
Synthesis of imidazole BA analogues [61]. Reagents and conditions: (i) CDI, dry THF, N2, reflux, 8–9 h; (ii) DDQ, dioxane, N2, reflux, 15 h; (iii) O2, t-BuOK, t-BuOH, 40ºC, 2 h.
Synthesis of imidazole BA analogues [61]. Reagents and conditions: (i) CDI, dry THF, N2, reflux, 8–9 h; (ii) DDQ, dioxane, N2, reflux, 15 h; (iii) O2, t-BuOK, t-BuOH, 40ºC, 2 h.