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. 2021 Feb 19;22(4):2051. doi: 10.3390/ijms22042051
5-methylTHF 5:10-methylenetetrahydrofolate to 5-methyltetrahydrofolate
ATP Adenosine triphosphate
SAHH AdoHcy hydrolase
AGEs Advanced glycation end products
AD Alzheimer’s disease
APP Amyloid precursor
ADMA Asymmetric dimethylarginine
BHMT Betaine-homocysteine methyltransferase
BBB Blood–brain barrier
CAA Cerebral amyloid angiopathy
CBF Cerebral blood flow
SVD Cerebral small vessel disease
CSF Cerebrospinal fluid
CRP C-reactive protein
cGMP Cyclic guanosine monophosphate
cGMP Cyclic guanosine-30,5-monophosphate
CBS Cystathionine β-synthase
CSE Cystathionine γ-lyase
DDAH Dimethylarginine dimethylaminohydrolase
DUSPs Dual-specificity phosphatases
HERP Endoplasmic protein
ER Endoplasmic reticulum
eNOS Endothelial NO synthase
EDHF Endothelium-derived hyperpolarizing factors
ERK Extracellular signal-regulated kinase
ERM Ezrin, radixin, and moesin
GABA Gamma-amino butyric
PQC Global cellular protein quality control
Hcy Homocysteine
HERP Hcy-induced Endoplasmic Reticulum Protein
HHcy hyperhomocysteinemia
P-tau Hyperphosphorylated tau protein
HIF 1 Hypoxia-inducible factor 1
ICAM-1 Intercellular adhesion molecule-1
IL-6 Interleukin-6
LOX Lectin-like low-density lipoprotein
MMP Matrix-metalloprotease
MST 3-mercaptopyruvate sulfurtransferase
MAT Methionine adenosyltransferase
MTR Methionine synthase
MetRS Methionyl-tRNA synthase
MT Methyltransferase
PPM1 and PPM2A Methyltransferase systems
MAP Mitogen-activated protein kinases
MLCP Myosin light-chain phosphatase
NADPH Nicotinamide Adenine Dinucleotide Phosphate Hydrogen
NO Nitric oxide
NOS Nitric oxide synthase
NMDA N-methyl D-Aspartate
SID N-[(1,1-dimethyl ethoxy)carbonyl]-L-tryptophan-2-[[[2-[(2- ethyl phenyl)amino]-2-oxoethyl]thio]carbonyl]hydrazide
NFK-Beta Nuclear factor kappa light-chain enhancer of activated B cells
PVS Perivascular spaces
PAI-1 Plasminogen activator inhibitor-1
PHOX Phagocytic NADPH oxidase
PC Phosphatidylcholines
PEMT Phosphatidylethanolamine N-methyltransferase
PS1 Presenilin 1
PRMTs Protein arginine N-methyltransferases
PKM-2 Pyruvate kinase muscle isoenzyme 2
ROS Reactive oxygen species
ROCK Rho-associated protein kinase
SAM S-adenosyl methionine
AdoHcy S-adenosylhomocysteine
SAH S-adenosyl-L-homocysteine
AdoMet S-adenosylmethionine
STATs Signal transducer and activator of transcription proteins
STAT3 Signal transducer and activator of transcription 3
SIRT1-HSF1 axis Sirtuin/heat shock factor 1/heat shock protein axis
sTM Soluble thrombomodulin
sVAD Subcortical vascular dementia
SOD Superoxide dismutase
DNMT Toll like receptor/NF-KB-DNA methyltransferase
TLR Toll-like receptor
UPS Ubiquitin-proteasome system
UPR Unfolded protein response
VEGF Vascular endothelial growth factor
Cbl Vitamin B12