Table 4.
NT-proBNP and CRP readings for the CHF patients according to NYHA groups.
| Readings | I NYHA (n = 26) |
II NYHA (n = 78) |
III NYHA (n = 54) |
IV NYHA (n = 27) |
p Value |
|---|---|---|---|---|---|
| NT-proBNP, ng/L (median, min-max) |
222.9 (29.0–2160) a,b,c | 702 (45.2–6501) | 1496.5 (159–15377) | 2095.5 (450.9–7649) | <0.007 * |
| CRP, mg/L (median, min-max) |
3.12 (1.0–15.50) | 3.13 (0.60–40.80) | 3.15 (1.00–41.00) | 4.62 (2.20–90.50) | 0.668 * |
| Fibrinogen, g/L (median, min-max) |
3.59 (2.6–5.3) | 3.60 (2.2–7.9) | 3.74 (2.3–7.5) | 4.00 (2.7–5.1) | 0.395 * |
| Cortisolm, nM (mean ± sd) |
470.35 ± 165.71 | 476.32 ± 157.17 | 480.01 ± 166.90 | 439.14 ± 160.10 | 0.995 |
| Cortisole, nM (mean ± sd) |
349.31 ± 154.37 | 369.86 ± 122.54 | 370.18 ± 119.49 | 440.87 ± 143.39 | 0.059 |
| Cortisolm-cortisole, nM (mean ± sd) |
121.04 ± 179.16 c,d | 78.14 ± 158.19 | 108.82 ± 161.89 | 90.18 ± 162.09 | <0.021 |
| Platelet aggregation, ADP,% (mean ± sd) |
68.33 ± 9.66 b | 71.50 ± 11.26 f | 75.38 ± 8.94 | 70.62 ± 12.11 | <0.023 |
| Platelet aggregation, ADR,% ( mean± sd) |
72.88 ± 11.91 a,b | 80.94 ± 9.65 | 81.02 ± 11.85 | 78.42 ± 15.46 | 0.002 |
Note: *—The comparisons were made using the Welch’s test. ANOVA was used for other comparisons. Note: a—statistically significant difference between NYHA I and NYHA II patients; b—statistically significant difference between NYHA I and NYHA III patients; c—statistically significant difference between NYHA I and NYHA IV patients; d—statistically significant difference between NYHA III and NYHA IV patients; f—statistically significant difference between NYHA II and NYHA III patients; MPV—mean platelet volume; CRP—C reactive protein; Cortisolm—morning cortisol concentration; Cortisole—evening cortisol concentration; Cortisolm-e—difference between morning and evening cortisol concentrations; ADP—adenozinediphosphate; ADR—adrenaline; NT-proBNP—N-terminal pro b-type natriuretic peptide.