Table 2.
PTH tertile 1 (n = 206) | PTH tertile 2 (n = 208) | PTH tertile 3 (n = 208) | |
---|---|---|---|
PTH (pmol/L) | 3.0 (3.0–3.1) | 4.3 (4.2–4.3)a | 6.5 (6.3–6.8)a,b |
Calcium (mmol/L) | 2.3 (2.3–2.3) | 2.3 (2.3–2.3) | 2.3 (2.3–2.3) |
Phosphate (mmol/L) | 1.0 (1.0–1.0) | 1.0 (1.0–1.0) | 0.9 (0.9–0.9)a,b |
25(OH)D3 (nmol/L) | 82 (76–88) | 70 (65–75)a | 63 (59–67)a |
1,25(OH)2D3 (pmol/L) | 107 (102–112) | 108 (103–113) | 110 (105–115) |
Haemoglobin (g/L) | 144 (142–146) | 144 (143–146) | 145 (143–146) |
C-reactive protein (mg/L) | 1.6 (1.2–2.2) | 1.6 (1.3–1.8) | 1.8 (1.5–2.2) |
Creatinine (μmol/L) | 74 (73–76) | 73 (72–75) | 74 (72–76) |
Cystatin C (mg/L) | 0.8 (0.8–0.8) | 0.9 (0.8–0.9)a | 0.9 (0.8–0.9)a |
Uric acid (μmol/L) | 290 (280–300) | 307 (297–317) | 313 (302–325)a |
ALT (U/L) | 27 (25–29) | 30 (27–33) | 33 (30–37)a |
ALP (U/L) | 58 (56–60) | 60 (58–63) | 66 (64–69)a,b |
Sodium (mmol/L) | 140 (140–1416) | 140 (140–141) | 141 (140–141) |
Potassium (mmol/L) | 3.8 (3.8–3.9) | 3.8 (3.8–3.9) | 3.8 (3.7–3.8) |
Renin (ng Ang I/mL/h) | 1.0 (0.9–1.1) | 1.0 (0.8–1.1) | 1.0 (0.8–1.1) |
Aldosterone (pmol/L) | 518 (470–567) | 493 (458–528) | 519 (449–588) |
Total cholesterol (mmol/L) | 5.0 (4.8–5.1) | 5.2 (5.1–5.4)a | 5.3 (5.1–5.4)a |
Triglycerides (mmol/L) | 1.2 (1.0–1.3) | 1.2 (1.2–1.3) | 1.4 (1.2–1.6)a |
HDL cholesterol (mmol/L) | 1.6 (1.6–1.7) | 1.6 (1.5–1.7) | 1.5 (1.5–1.6) |
LDL cholesterol (mmol/L) | 2.9 (2.7–3.0) | 3.1 (3.0–3.2)a | 3.2 (3.1–3.3)a |
Glucose (mmol/L) | 5.3 (5.3–5.4) | 5.5 (5.4–5.6)a | 5.5 (5.5–5.6)a |
Insulin (mU/L) | 7.5 (7.8–8.3) | 8.2 (7.3–9.0) | 11.4 (7.5–15.2) |
Estimated GFR (mL/min/1.73 m2) | 103 (100–105) | 97 (95–100)a | 96 (94–99)a |
QUICKI | 0.365 (0.356– 0.374) | 0.354 (0.349–0.359) | 0.349 (0.342–0.356)a |
Results shown as mean (95% CI of the mean). Due to missing values, all blood and plasma biochemistry results were available in tertile 1 for 197 subjects, in tertile 2 for 194 subjects, and in tertile 3 for 186 subjects.
aP < 0.05 vs tertile 1; bP < 0.05 vs tertile 2.
1,25(OH)2D3, 1,25-dihydroxyvitamin D3; 25(OH)D3, 25-hydroxyvitamin D3; ALP, alkaline phosphatase; ALT, alanine aminotransferase; GFR, glomerular filtration rate (estimated by cystatin C based CKD-EPI formula); HDL, high-density lipoprotein; LDL, low-density lipoprotein; PTH, parathyroid hormone; QUICKI, quantitative insulin sensitivity check index.