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. 2021 Feb 17;13(2):312. doi: 10.3390/v13020312

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Inhibitory effect of the 22 selected compounds on the activation of the MBL complement pathway. Test compounds were dissolved in pooled normal human serum at 100µM and tested in the Wieslab ELISA-based kit to assess their potential to inhibit the complement activation of the MBL pathway. The MBL pathway activation detected by anti-C5b-9 ALP antibody in samples treated with DMSO was set as 100%. All data shown represent the means ± SD of data tested in duplicate. Data from each compound was analyzed by a Student’s t-test versus that of DMSO-treated control. * p < 0.05; ** p < 0.01; *** p < 0.001.