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. 2021 Feb 18;26(4):1055. doi: 10.3390/molecules26041055

Scheme 10.

Scheme 10

Synthesis of 6-chloro-7-fluoroquinoxaline derivatives (35) with reagents and conditions: (a) HOAc/Ac2O, (b) 70% HNO3/concentrated H2SO4 (c) concentrated H2SO4, (d) Zn/Hydrazinium monoformate; (e) (i) C2H5OH, (ii) CH3OH, (iii) HOAc:CH3OH (3:2)/NaOAc, (iv) HOAc/NaOAc.