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. 2021 Feb 17;2021:20-0122. doi: 10.1530/EDM-20-0122

Table 2.

Recommended protocol using the AVP (arginine vasopressin) Infusion Sliding Scale.

Urine output, mL/kg/h Action taken
<2 Stop infusion till urine output is 3–4 mL/kg/h
2–3 Reduce infusion rate by 25%
3–4 Maintain infusion rate
4–5 Increase infusion rate by 25%
>5 Increase infusion rate by 50%

Aim for urine output 3–4 mL/kg/h, however, this target will be dependent on fluid balance. Calculate hourly urine output to enable titration of AVP to be done hourly. Size of increment/decrement may need to be altered depending on patient’s sensitivity to desmopressin.