Table 1.

Characteristics of patients in the pre-treated and untreated group.

Variables	Untreated (n = 23)	Pre-treated (n = 17)	P value
Age (years)	48.0 ± 13.0	51.2 ± 13.8	0.455
Female sex	15/23	12/17	0.720
Diabetes	2/23	4/17	0.194
Hypertension	6/23	6/17	0.530
Heart disease	1/23	1/17	0.826
Obesity	3/23	2/17	0.904
SAS	5/23	3/17	0.749
Pituitary apoplexy	1/23	0/17	0.384
Visual involvement	5/23	0/17	0.040
Headache	9/23	1/17	0.030
Hypopituitarism	6/23	3/17	0.527
Presurgical GH	13.0 ± 17.5	10.9 ± 8.7	0.641
Presurgical IGF1	693.0 ± 316.8	653.1 ± 260.1	0.674
Very large PA	4/23	0/17	0.070
Tumor size at diagnosis (mm)	18.3 ± 8.5	15.1 ± 7.7	0.223
Knosp grade 3–4	11/23	4/17	0.117

Presurgical GH and IGF1 are expressed in ng/mL and refers to the values previous to SRL treatment. Bold values indicate statistical significance.

SAS, sleep apnoea syndrome.