Table 3.

Differential features of patients treated with high doses of SRL and those untreated or treated with low doses.

Variable	High doses (n = 11)	Low doses and untreated (n = 29)	P value
Age (years)	51.4 ± 13.1	48.6 ± 13.5	0.556
Female sex	7/11	20/29	0.748
Visual involvement	0/11	5/29	0.141
Hypopituitarism	5/11	14/29	0.873
Presurgical GH	9.4 ± 8.2	13.2 ± 16.0	0.466
Presurgical IGF1	608 ± 274.6	701.8 ± 297.7	0.370
Tumor size (mm)	14.2 ± 7.8	18.0 ± 8.3	0.199
Very large PA	0/11	4/29	0.194
Hard consistency	1/11	10/29	0.108
Fibrosis grade 2–3a	2/8	5/11	0.361

^aInformation about the grade of fibrosis was available only in 19 patients.