Table 3.
Percentage (95% CI) positive agreement between the macimorelin GHST and the ITT at different cutpoints among participants with a positive finding for each ITT cutpoint.
| Macimorelin cutpoint, ng/mL | ITT cutpoint, ng/mL | |||
|---|---|---|---|---|
| 2.8 (n = 62/140) | 4.0 (n = 67/140) | 5.1 (n = 74/140) | 6.5 (n = 82/140) | |
| 2.8 | 87.1% (76.2–94.3%) | 80.6% (69.1–89.2%) | 74.3% (62.8–83.8%) | 68.3% (57.1–78.1%) |
| 4.0 | 88.7% (78.1–95.3%) | 82.1% (70.8–90.4%) | 78.4% (67.3–87.1%) | 72.0% (60.9–81.3%) |
| 5.1 | 90.3% (80.1–96.4%) | 86.6% (76.0–93.7%) | 82.4% (71.8–90.3%) | 75.6% (64.9–84.4%) |
| 6.5 | 93.6% (84.3–98.2%) | 89.6% (79.7–95.7%) | 87.8% (78.2–94.3%) | 81.7% (71.6–89.4%) |
Results in italics are based on using the same cutpoints for macimorelin and the ITT. n = number of participants with a positive finding using the specified ITT cutpoint.
GHST, growth hormone stimulation test; ITT, insulin tolerance test.
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