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. Author manuscript; available in PMC: 2022 Feb 10.
Published in final edited form as: J Control Release. 2020 Dec 13;330:173–184. doi: 10.1016/j.jconrel.2020.12.007

Fig. 4. In vitro assay for the silencing of the oncogenic protein ADAM10 and the drug transporter MDR1 (P-gp) by 6WJ/HTL/miR122 nanoparticles.

Fig. 4.

A. qRT-PCR showing effect of miR122 knock-down on ADAM 10 gene expression. B. Western blot showing the knock-down of ADAM10 and MDR1 proteins expression. C. Quantification of ADAM 10 & MDR1 proteins expression from western blot. (n = 3 biologically independent animals, statistics was calculated by two-tailed unpaired t-test presented as mean ± SD, *p < 0.05, **p < 0.01, ****p < 0.0001).