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. Author manuscript; available in PMC: 2022 Mar 1.
Published in final edited form as: Bioorg Med Chem. 2021 Jan 22;33:116037. doi: 10.1016/j.bmc.2021.116037

Figure 2. The structure of IFNα and the introduced N-glycosylation site.

Figure 2.

A) The structure of human IFNα (PDB code 2hym). The two positions chosen for site-directed mutagenesis are highlighted. Mutagenesis at P4 is shown in blue and at Q158 in red. B) The engineered N-glycosylation sites. The modified amino acids in both the mutants are highlighted in red.