Figure 1. . Box plot distributions of selected methylated DNA marker candidates in colorectal tissues from Lynch syndrome and sporadic patients from biological validation phase.

(A) MDMs showing similarly high neoplasm discrimination across Lynch syndrome and sporadic patients. (B) MDMs showing relatively higher neoplasm discrimination in Lynch syndrome patients. (C) MDMs showing relatively higher discrimination in sporadic patients.

A: Adenoma; C: Colorectal cancer; MDM: Methylated DNA marker; N: Normal.