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. 2021 Mar 2;22:102. doi: 10.1186/s12859-021-04040-8

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 3 — Correlation between PTGR1 transcript level (Y axis) and observed or predicted LP-184 IC50s (X axis). a PTGR1 gene expression correlation with actual IC50 from NCI-60 solid tumor cell lines (excluding blood) PTGR1 expression correlation from 52 NCI-60 solid tumor cell lines with LP184 drug sensitivity shows strong and significant (p value 1.539e−11) Pearson correlation (correlation coefficient r = 0.775). b PTGR1 gene expression correlation with actual IC50 from all NCI-60 cancer cell lines (including blood). c PTGR1 gene expression correlation with predicted IC50 from CCLE solid tumor cell lines (excluding blood and lymph). d PTGR1 gene expression correlation with predicted IC50 from all CCLE cell lines (including blood and lymph)