Skip to main content
. 2021 Feb 17;118(8):e2017889118. doi: 10.1073/pnas.2017889118

Fig. 5.

Fig. 5.

PLSR of week 9 samples identifies early factors that are positively correlated and inversely correlated with healing. (A) Heatmap of z-scored week 9 immune cell and cytokine levels, sorted by week 20 bone volumes. (B) PLSR analysis established LV1, which describes samples along the continuum of healing responses. (C) This LV1 defines the profile of week 9 immune cells and cytokines correlated with healing and shows that MDSCs, monocytes, IP-10, and IL-1β were most negatively correlated with healing, while B cells, T helper cells, and IL-13 were most positively correlated with healing.