Table 1.
Univariate and multivariate analysis
| Characteristic | Univariate analysis | Multivariable analysis | |||
|---|---|---|---|---|---|
| HR(95%CI) | P value | HR(95%CI) | P value | ||
| Age | < 65 vs > =65 | 1.48 (0.64–3.45) | 0.361 | 1.3 (0.55–3.07) | 0.56 |
| Gender | Female vs Male | 0.78 (0.35–1.71) | 0.534 | 0.72 (0.31–1.66) | 0.44 |
| Site | Left vs Right | 0.85 (0.29–2.49) | 0.769 | 1.81 (0.53–6.16) | 0.34 |
| T | T1/T2 vs T3/T4 | 1.08 (0.37–3.16) | 0.887 | 1.11 (0.36–3.45) | 0.853 |
| N | N0/N1 vs N2 | 0.68 (0.30–1.53) | 0.347 | 0.82 (0.35–1.92) | 0.649 |
| Mismatch Repair Status | Proficient vs Deficient | – | 0.997 | – | – |
| MMR genetic variants | Mutation vs Wild | 1.03 (0.39–2.7) | 0.954 | 0.94 (0.34–2.61) | 0.914 |
| Risk group | G1 vs G2 | 5.80 (2.30–14.61) | 0.000187 | 7.46 (2.48–18.56) | 0.000192 |
Abbreviations: T tumor invasion, N lymph node, MSI microsatellite instability, G1 low-risk group, G2 high-risk group, HR hazard ratio, MMR mismatch repair