Table 6.
Correlations between total tau levels and behavioral parameters in the elevated zero maze
| Elevated zero maze | ||||||
|---|---|---|---|---|---|---|
| Total tau | Pearson | Kendall's tau-b | Spearman's rho | |||
| Correlation coefficient | p value | Correlation coefficient | p value | Correlation coefficient | p value | |
| Left anterior cortex | ||||||
| Move distance | − .057 | .875 | − .067 | .788 | .018 | .960 |
| Open arm time | .040 | .913 | .022 | .929 | .127 | .726 |
| Cross arm latency | .230 | .522 | .022 | .929 | .055 | .881 |
| Right anterior cortex | ||||||
| Move distance | − .396 | .257 | − .333 | .180 | − .455 | .187 |
| Open arm time | − .390 | .265 | − .244 | .325 | − .370 | .293 |
| Cross arm latency | − .114 | .753 | .289 | .245 | .358 | .310 |
| Left Hippocampus | ||||||
| Move distance | .508 | .134 | .600 | .016 | .770 | .009 |
| Open arm time | .696 | .025 | .511 | .040 | .697 | .025 |
| Cross arm latency | .076 | .834 | − .289 | .245 | − .394 | .260 |
| Right Hippocampus | ||||||
| Move distance | .550 | .100 | .467 | .060 | .588 | .074 |
| Open arm time | .526 | .119 | .378 | .128 | .503 | .138 |
| Cross arm latency | .261 | .467 | − .156 | .531 | − .152 | .676 |
| Left Amygdala | ||||||
| Move distance | .158 | .662 | .022 | .929 | .018 | .960 |
| Open arm time | .189 | .601 | .111 | .655 | .152 | .676 |
| Cross arm latency | − .559 | .093 | − .244 | .325 | − .297 | .405 |
| Right Amygdala | ||||||
| Move distance | .278 | .437 | .244 | .325 | .382 | .276 |
| Open arm time | − .048 | .894 | − .022 | .929 | .018 | .960 |
| Cross arm latency | .361 | .306 | − .111 | .655 | − .115 | .751 |
| Left Posterior Cortex | ||||||
| Move distance | .361 | .305 | .333 | .180 | .345 | .328 |
| Open arm time | .080 | .826 | .067 | .788 | .127 | .726 |
| Cross arm latency | − .272 | .448 | − .378 | .128 | − .455 | .187 |
| Right Posterior Cortex | ||||||
| Move distance | − .629 | .051 | − .511 | .040 | − .697 | .025 |
| Open arm time | − .489 | .151 | − .244 | .325 | − .382 | .276 |
| Cross arm latency | − .126 | .729 | .200 | .421 | .236 | .511 |
Total tau levels were previously determined by Western blotting at 40 weeks after blast exposure [21]. Total tau levels were correlated with three behavioral parameters in the elevated zero maze (move distance, open arm time and cross arm latency) previously found to be affected in blast-exposed animals at 30 weeks following blast exposure [80]. Five blast and five control animals were analyzed. Correlations with p values less than 0.05 are indicated in bold