Table 2.

Histomorphology and immunophenotypic profile of DDLPS PDX models

	LS-BZ-1	LS-GD-1	LS-BP-1
Human tumor	DDLPS, G3, myogenic dedifferentiation	DDLPS, G3, rhabdmyoblastic dedifferentiation	DDLPS, G3, myogenic dedifferentiation
H&E	Spindle cells and epitheliod cells	Spindle cells organized in fascicles, and rhabdoid cells	Spindle cells with small nuclei
CK1	Negative	Negative	Negative
CK3	Negative	Negative	Negative
EMA	Negative	Negative	Negative
Myogenin	Negative	Positive, diffuse	Negative
Actin 1A4	Negative	Positive, focal	Negative
Desmin	Negative	Positive, diffuse	Negative
H3K27me3	Positive	Positive	Positive
MDM2	Positive	Positive	Positive