Table 1.

Characteristic of included studies

Authors	Year	Sample size	Age	Dose	Duration	Baseline values
						FBS	TC	TG	LDL	HDL	HgA1C	BMI
Bhatt et al.[25]	2013	59	57.5	500	12	NR	196.83	160.31	96.67	51.98	NR	25.8
El Al et al.[26]	2018	20	51.02	1000	12	154.88	209.75	131.5285	122.45	22.91	8.065	27.87
Evans et al.[27]	2003	20	53.2	1000	6	157.5	210.75	103.24	129.54	27.65	8.45	28.9
Ghaffari et al.[28]	2015	30	51.9	800	8	176.93	227.35	NR	159.93	43.48	NR	NR
Gilliani et al.[29]	2017	210a	37.8	500	52	142.06	233.59	84.77	120.08	37.9	9.15	23.90
Hemed et al.[30]	2016	39	52	1000	12	143.81	239.38	123.94	157.12	34.35	7.29	NR
Mahmoudabadi et al.[31]	2011	23	51.45	200	8	154.02	163.6	148.92	100.7	40.12	7.91	29.1
Rafighi et al.[32]	2011	58	53.82	266.7	12	151.75	191.21	122.24	129.62	35.11	8.39	29.86
Ragheb et al. [33]	2020	27	55.16	500	8	143.89	230.72	105.22	138.41	62.63	8.64	33.57
Sanguanwong et al.[34]	2016	100	57.75	1000	8	148.63	172.05	75.13	89.73	41.34	7.72	25.74
Tousoulis et al.[35]	2007	20a	60	2000	4	NR	182.13	81.33	103.24	32.09	6.48	28.5

BMI body mass index, FBS fasting blood sugar, HDL: high density lipoprotein, HgA1C hemoglobin A1C, LDL low density lipoprotein, TC total cholesterol, TG total triglycerides, NR not reported

^aThe sample size of the studies were corrected based on the number of experimental arms as indicated in methodology