Table 3.
Frequencies of micronucleated immature erythrocytes (MN-PCE) in female F0 Sprague Dawley rats administered deoxynivalenol for 6 weeks starting on gestation day 6 by oral gavage1
| Dose (mg/kg/day) | MN-PCE/1000 | %PCE |
|---|---|---|
| 02 | 1.13 ± 0.14 | 0.59 ± 0.09 |
| 0.03 | 1.00 ± 0.15 | 0.88 ± 0.08 |
| 0.1 | 1.21 ± 0.11 | 0.58 ± 0.08 |
| 0.3 | 0.96 ± 0.09 | 0.70 ± 0.13 |
| 1.0 | 1.13 ± 0.37 | 0.73 ± 0.16 |
| 3.0 | 0.92 ± 0.12 | 0.83 ± 0.05 |
| Trend test P3 = | 0.776 | 0.422 |
1
Six animals per treatment group; 20,000 PCE scored per animal using flow cytometry
2
Deionized water
3
Trend test; significance set at P < 0.025