Table 2.
Paraclinical features of the study population, overall and according to vital status.
| Variable | N | Overall (N = 2878) | Alive (n = 2503) | Died in hospital (n = 360) | P |
|---|---|---|---|---|---|
| Laboratory values | |||||
| Haemoglobin (g/dL) | 2835 | 13.1 ± 2.0 | 13.2 ± 1.9 | 12.7 ± 2.2 | < 0.001 |
| Leucocytes (g/L) | 2827 | 7.3 ± 5.1 | 7.1 ± 4.6 | 9.0 ± 7.8 | < 0.001 |
| Lymphocytes (g/L) | 2785 | 1.3 ± 3.5 | 1.3 ± 2.7 | 1.6 ± 6.7 | 0.07 |
| Platelets (g/L) | 2807 | 220 ± 99 | 223 ± 99 | 203 ± 101 | 0.001 |
| GFR (mL/min/m2) | 2829 | 81.6 ± 29.5 | 84.6 ± 28.1 | 61.8 ± 31.3 | < 0.001 |
| Aspartate aminotransferase (IU/L) | 2608 | 53.7 ± 69.0 | 50.9 ± 62.5 | 72.8 ± 102 | < 0.001 |
| Total bilirubin (mg/L) | 2423 | 10.9 ± 13.4 | 10.6 ± 13.4 | 12.2 ± 10.2 | 0.04 |
| Gamma glutamyl transferase (IU/L) | 2301 | 92 ± 31 | 90 ± 127 | 106 ± 156 | 0.04 |
| Alkaline phosphatase (IU/L) | 2366 | 90 ± 119 | 88 ± 120 | 108 ± 108 | 0.003 |
| Phosphoraemia (mmol/L) | 1077 | 1.0 ± 0.3 | 0.97 ± 0.3 | 1.1 ± 0.4 | < 0.001 |
| Corrected serum calcium (mmol/L) | 1258 | 2.4 ± 0.2 | 2.4 (0.2) | 2.5 (0.3) | 0.003 |
| Albumin (g/L) | 1642 | 31.8 ± 6.5 | 32.1 ± 6.5 | 29.8 ± 6.2 | < 0.001 |
| C-reactive protein (mg/L) | 2758 | 90.3 ± 77.1 | 85.7 ± 74.3 | 121.0 ± 85.9 | < 0.001 |
| Fibrinogen (g/L) | 1379 | 6.0 ± 1.7 | 6.0 ± 1.7 | 6.0 ± 1.5 | 0.91 |
| Prothrombin rate (%) | 2215 | 85.0 ± 18.1 | 85.9 ± 17.6 | 78.4 ± 20.3 | < 0.001 |
| D-dimer (μg/L) | 1156 | 1644 ± 3633 | 1481 ± 2407 | 3025 ± 8624 | 0.051 |
| pH | 2006 | 7.5 ± 0.1 | 7.5 ± 0.1 | 7.4 ± 0.1 | < 0.001 |
| Lactates (mmol/L) | 1756 | 1.4 ± 1.0 | 1.4 ± 0.8 | 1.9 ± 1.6 | < 0.001 |
| Elevated BNP or NT-pro-BNPa | 1778 | 943 (53.0) | 702 (47.2) | 234 (83.6) | < 0.001 |
| Troponin elevationb | 1763 | 572 (32.4) | 442 (28.8) | 127 (58.5) | < 0.001 |
| qSOFA score ≥ 2 | 2109 | 1298 (61.5) | 1094 (59.8) | 196 (73.4) | < 0.001 |
| Sepsis-induced coagulopathy score > 1 | 1672 | 1135 (67.9) | 969 (66.2) | 162 (80.2) | < 0.001 |
| Electrocardiogram | |||||
| Heart rate (beats/min) | 2624 | 86.6 ± 17.9 | 86.5 ± 17.6 | 87.8 ± 20.2 | 0.16 |
| Complete bundle-branch block | 2121 | 164 (7.7) | 122 (6.5) | 42 (17.4) | < 0.001 |
| Non-sinus rhythm | 2312 | 260 (11.2) | 196 (9.7) | 64 (23.3) | < 0.001 |
| Corrected QT-segment (ms) | 1162 | 435 ± 51 | 433 ± 50 | 458 ± 55 | < 0.001 |
| Chest computed tomography | |||||
| Parenchymal involvement | 2247 | < 0.001 | |||
| Mild (< 30) | 953 (42.4) | 874 (43.9) | 77 (31.2) | ||
| Moderate (30 − 50) | 864 (38.5) | 764 (38.4) | 96 (38.9) | ||
| Severe (> 50) | 430 (19.1) | 353 (17.7) | 74 (30.0) |
Data are expressed as number (%) or mean ± SD. Fifteen patients with unknown final status were excluded from the analysis. BNP: B-type natriuretic peptide; GFR: glomerular filtration rate; NT − pro-BNP: N-terminal pro-B-type natriuretic peptide; qSOFA: quick Sequential Organ Failure Assessment.
a
BNP > 50 pg/mL or NT-pro-BNP > 300 pg/mL.
b
Above each centre threshold.