Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Mar 2;28(6):3325–3332. doi: 10.1016/j.sjbs.2021.02.077

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 Published by Elsevier B.V. on behalf of King Saud University.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Fig. 2 — Spike glycoprotein homo-trimer structure modeling. SWISS model was used to get the best template and the fitting model (GQME = 0.75, QMEAN = -2.07, 0.94 coverage, 95% identity for hCoV-19/SA/KAIMRC-Alghoribi and GQME = 0.78, QMEAN = -3.87, 0.94 coverage and 76.73% identity for bat-ST-COVZC45) followed by importing the model to QIAGEN CLC Main Workbench V20.0 to obtain the final homo-trimer of (A) hCoV-19/SA/KAIMRC-Alghoribi and (B) bat-ST-COVZC45 and (C) models alignment. Three chains were observed for each of hCoV- 19 and bat-SL-CoV, thus each chain was aligned on basis of their amino acid sequence and their 3D structure, involving (D) Chain A, (E) Chain B and (F) Chain C.

Fig. 2 — Spike glycoprotein homo-trimer structure modeling. SWISS model was used to get the best template and the fitting model (GQME = 0.75, QMEAN = -2.07, 0.94 coverage, 95% identity for hCoV-19/SA/KAIMRC-Alghoribi and GQME = 0.78, QMEAN = -3.87, 0.94 coverage and 76.73% identity for bat-ST-COVZC45) followed by importing the model to QIAGEN CLC Main Workbench V20.0 to obtain the final homo-trimer of (A) hCoV-19/SA/KAIMRC-Alghoribi and (B) bat-ST-COVZC45 and (C) models alignment. Three chains were observed for each of hCoV- 19 and bat-SL-CoV, thus each chain was aligned on basis of their amino acid sequence and their 3D structure, involving (D) Chain A, (E) Chain B and (F) Chain C.