Table 1.
Baseline patient characteristics of the 2 treatment methods
| Parameters | Laparoscopic resection (n = 251) | p-RFA (n = 315) | p value |
|---|---|---|---|
| Age, years (mean ± SD) | 57.5±9.3 | 60.8±9.6 | <0.001 |
| Gender (n, M:F) | 199:52 | 227:88 | 0.050 |
| Etiology, n (%) | |||
| HBV | 196 (78.1) | 234 (74.3) | 0.730 |
| HCV | 21 (8.4) | 34 (10.8) | |
| Alcoholic | 29 (11.5) | 40 (12.7) | |
| Others | 5 (2.0) | 7 (2.2) | |
| Tumor size, cm (mean ± SD) | 2.13±1.44 | 1.69±0.50 | <0.001 |
| Albumin, mg/dL (mean ± SD) | 4.36±0.38 | 4.11±0.45 | <0.001 |
| Total bilirubin, mg/dL (mean ± SD) | 0.76±0.37 | 0.81±0.44 | 0.146 |
| Prothrombin activity (INR, mean ± SD) | 1.04±0.08 | 1.10±0.11 | <0.001 |
| AFP, ng/mL (mean ± SD) | 218.4±904.2 | 72.9±211.6 | 0.013 |
| Platelet count, K/mm3 (mean ± SD) | 168.4±53.5 | 130.2±50.9 | <0.001 |
| Tumor location, n (%) | |||
| Perivascular alone | 33 (13.1) | 64 (20.3) | <0.001 |
| Subcapsular alone | 135 (53.8) | 93 (29.5) | |
| Non-subcapsular and non-perivascular | 52 (20.7) | 144 (45.7) | |
| Perivascular and subcapsular | 31 (12.4) | 14 (4.5) | |
| Tumor in postero-superior portion, n (%) | 94 (37.5) | 162 (51.4) | 0.001 |
p-RFA, percutaneous radiofrequency ablation; SD, standard deviation; HBV, hepatitis B virus; HCV, hepatitis C virus; INR, international normalized ratio; AFP, alpha-fetoprotein. Tumor in postero-superior portion of the liver includes tumors in segments 1, 7, 8, and 4a.