Table 2.
Levels of metabolic syndrome-related biomarkers among severe SARS-CoV-2 infection cases and hospital-based controls
| Biomarker | Unmatched |
Matched |
||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| N | Cases | N | Controls | P | n | Cases | n | Controls | P | |
| Total cholesterol (mg/dl) | 1,057 | 209 (64) | 3,367 | 211 (60) | 0.07 | 676 | 213 (59) | 1,438 | 212 (61) | 0.64 |
| Triglycerides (mg/dl) | 1,050 | 150 (109) | 3,365 | 132 (103) | 2.8 × 10−8 | 670 | 139 (95) | 1,437 | 129 (94) | 3.1 × 10−03 |
| LDL-cholesterol (mg/dl) | 1,053 | 131 (50) | 3,362 | 131 (47) | 0.75 | 672 | 133 (45) | 1,436 | 131 (46) | 0.13 |
| Apolipoprotein B (mg/dl) | 1,048 | 100 (35) | 3,352 | 99 (32) | 0.53 | 670 | 101 (32) | 1,434 | 99 (32) | 0.06 |
| HDL-cholesterol (mg/dl) | 968 | 50 (18) | 3,087 | 53 (19) | 3.0 × 10−11 | 620 | 52 (18) | 1,438 | 54 (18) | 1.2 × 10−03 |
| ApoA1 (mg/dl) | 966 | 144 (35) | 3,069 | 149 (36) | 5.7 × 10−10 | 620 | 147 (35) | 1,438 | 151 (35) | 7.1 × 10−04 |
| Lipoprotein A (mg/dl) | 812 | 19.9 (52) | 2,664 | 19.5 (48) | 0.78 | 535 | 20.4 (55) | 1,136 | 21.1 (47) | 0.93 |
| Glucose (mg/dl) | 965 | 90 (15) | 3,087 | 89.6 (14) | 0.16 | 618 | 89 (14) | 1,438 | 89 (13) | 0.09 |
| HbA1c (%) | 1,064 | 5.5 (0.5) | 3,355 | 5.4 (0.5) | 4.1 × 10−8 | 682 | 5.4 (0.5) | 1,347 | 5.4 (0.5) | 0.49 |
HbA1c, hemoglobin A1c.
Data are shown as medians and interquartile ranges in cases and controls for whom serum biomarker levels were available.
P values for differences between cases and controls were derived from Mann-Whitney U tests.