Table 4.

Clinicopathological and genetic profile of the cases with DICER1 somatic mutations

	TCGA-EM-A2CT	TCGA-EL-A3D5	TCGA-EL-A3GO
Age, years	20	44	31
Gender	female	female	female
Size, mm	11	60	32
Laterality	unilateral	n.a.	unilateral
Focality	unifocal	multifocal	unifocal
Variant type	OV-PTC	OV-PTC	FV-PTC
Presence of capsule	partially	n.a.	n.a.
Capsule invasion	No	n.a.	n.a.
Lymph node metastasis	0/5	15/30	0/4
Extranodal involvement	No	Yes	No
Angiolymphatic invasion	n.a.	No	n.a.
Minimal ETE	No	Yes	No
Additional genetic events	NRAS	TP53	other

PTC, papillary thyroid carcinoma; FV, follicular variant; OV oncocytic variant; ETE, extrathyroidal extension; n.a., not available.