Table 2.

All cause mortality by oxygen protocol. Values are numbers (percentages) unless stated otherwise

	High oxygen	Low oxygen	Unadjused odds ratio (95% CI)	P value	Adjusted odds ratio (95% CI)*	P value
All cause mortality†:	n=20 304	n=20 568
30 days	613 (3.0)	642 (3.1)	0.97 (0.86 to 1.08)	0.55	0.96 (0.86 to 1.08)	0.50
1 year	1726 (8.5)	1682 (8.2)	1.04 (0.97 to 1.12)	0.24	1.05 (0.97 to 1.13)	0.21
STEMI‡:	n=2031	n=2128
30 days	178 (8.8)	225 (10.6)	0.81 (0.66 to 1.00)	0.049	0.78 (0.63 to 0.97)	0.027
1 year	272 (13.4)	321 (15.1)	0.87 (0.73 to 1.04)	0.12	0.84 (0.70 to 1.01)	0.063
Non-STEMI‡:	n=5152	n=5066
30 days	187 (3.6)	176 (3.5)	1.05 (0.85 to 1.29)	0.67	1.02 (0.83 to 1.27)	0.84
1 year	555 (10.8)	512 (10.1)	1.07 (0.95 to 1.22)	0.27	1.07 (0.94 to 1.23)	0.31
Unstable angina:	n=1606	n=1678
30 days	13 (0.8)	22 (1.3)	0.61 (0.31 to 1.22)	0.17	0.59 (0.29 to 1.18)	0.14
1 year	65 (4.0)	76 (4.5)	0.89 (0.63 to 1.25)	0.50	0.85 (0.60 to 1.21)	0.36
Non-ACS:	n=9681	n=9838
30 days	174 (1.8)	175 (1.8)	1.01 (0.82 to 1.25)	0.92	1.04 (0.84 to 1.29)	0.71
1 year	702 (7.3)	648 (6.6)	1.11 (0.99 to 1.24)	0.067	1.16 (1.03 to 1.30)	0.013
Non-classified diagnosis:	n=1834	n=1858
30 days	61 (3.3)	44 (2.4)	1.42 (0.95 to 2.10)	0.081	1.45 (0.97 to 2.18)	0.072
1 year	132 (7.2)	125 (6.7)	1.08 (0.83 to 1.39)	0.58	1.09 (0.83 to 1.43)	0.54
Patients with first SpO2§:	n=10 137	n=10 293
30 days	293 (2.9)	315 (3.1)	0.94 (0.80 to 1.11)	0.47	0.91 (0.76 to 1.09)	0.31
1 year	945 (9.3)	923 (9.0)	1.04 (0.95 to 1.15)	0.38	1.03 (0.92 to 1.14)	0.64

ACS=acute coronary syndrome; NSTEMI=non ST elevation myocardial infarction; STEMI=ST elevation myocardial infarction; SpO₂=transcapillary oxygen saturation level.

^*Adjusted for age, sex, region, and diagnosis of acute coronary syndrome. Age is stratified at median age for study population.

^†Primary outcome.

^‡Prespecified secondary analyses.

^§First oxygen saturation level measured on ambulance arrival. Data are for 20 430 patients from the ambulance ACS pathway only.