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. 2021 Jan 7;37(1):18–25. doi: 10.1159/000514032

B Small overview of publications describing IFS

Reference (first author) IFS Positive IFS Proximal/distal Additional resection R0 resection 5-year OS
Otsuka, 2019 [44] 558 74 (13.3%) distal 53 (71.6%) 30 (56.6%) 31% EBDX, 67% PPPD
Zhang, 2018 [45] 215 80 (37.2%) proximal/distal 58 (72.5%) 29 (50%) 44.3%
Mantel, 2016 [43] 67 17 (25.3%) proximal 10 (58.8%) 3 (30%) 39%

EBDX, external bile duct resection; IFS, intraoperative frozen section; NA, not applicable; OS, overall survival; PPPD, pylorus-preserving pancreaticoduodenectomy.

a

Thirty-day mortality.

b

Median survival 33 months.

c

Postoperative mortality/5-year OS for total group of vascular resections (n = 42).