Skip to main content
. Author manuscript; available in PMC: 2022 Jan 1.
Published in final edited form as: J Am Geriatr Soc. 2020 Sep 25;69(1):255–263. doi: 10.1111/jgs.16836

Table 1.

Association between ATN-X Biomarkers and Delirium

Likely Association with Delirium Equivocal No Likely Association with Delirium
Neurodegeneration
IL-6
IL-8
C-reactive protein
Synaptic function (EEG and fMRI)		 Amyloid
S-100B
Vascular		 Tau
IL-1 beta
IL-10
Tumor necrosis factor-alpha

FTD, EC-CAM, synucleinopathy, and actigraphy studies were not included because there were less than 4 studies.

Only inflammatory biomarkers with 15 or more articles are included in this table.

Likely association with delirium was defined as > 50% of studies finding an association between the biomarker or category of biomarkers and the presence of delirium.

Equivocal was defined as 25–50% of studies finding an association between the biomarker or category of biomarkers and the presence of delirium.

No likely association with delirium was defined < 25% of studies finding an association between the biomarker or category of biomarkers and the presence of delirium.