Table 1.
Demographic and clinical characteristics at enrolment in the entire cohort and in the three groups.
| Variables* | Total cohort (n = 392) | No-poly RRMS (n = 219) | Minor-poly RRMS (n = 61) | Major-poly RRMS (n = 112) | p-value |
|---|---|---|---|---|---|
| Gender, n (%) | |||||
| Male | 137 (34.9) | 77 (35.2) | 24 (39.3) | 31 (27.7) | ns |
| Female | 255 (65.1) | 142 (64.8) | 37 (60.7) | 81 (72.3) | ns |
| Age | 41.1 ± 11.7 | 29.3 ± 9.9 | 35.7 ± 11.4 | 36.9 ± 11.7 | <0.05 |
| Smokers, n (%) | 119 (30.3) | 40 (18.3) | 27 (44.3) | 45 (40.2) | <0.05 |
| BMI (median, IQR) | 24 (21–27) | 22.7 (21–25.8) | 24.3 (21.8–26) | 26.7 (22.4–29) | <0.05 |
| EDSS (median, IQR) | 2.0 (1–2.5) | 2.0 (1–2.5) | 2.0 (1.0–3.0) | 2.0 (1.0–3.0) | ns |
| N. of relapses one year before diagnosis | 1.8 ± 1 | 1.9 ± 0.9 | 1.6 ± 0.9 | 1.6 ± 1 | <0.05 |
| N. MRI T2 weighted brain lesions | 2.7 ± 1.2 | 2.7 ± 1.2 | 2.5 ± 1.3 | 2.7 ± 1.2 | ns |
| N. MRI T1 Gad+ weighted brain lesions | 0.8 ± 1.8 | 0.9 ± 1.9 | 0.9 ± 1.7 | 0.7 ± 1.7 | ns |
BMI, body mass index; EDSS, Expanded Disability Status Scale; Gad+, Gadolinium; IQR, interquartile range; MRI, magnetic resonance imaging; n, number.
*
Data are expressed as mean ± standard deviation unless otherwise specified.