Table 4.

Variables in the Cox proportional hazard model for the time to first DMT discontinuation in the three groups.

	p-value	Exp(B)	CI 95.0% per exp(B)
			Lower	Upper
Gender	0.624	1.093	0.765	1.562
Age	0.064	0.984	0.966	1.001
Lag time (between onset and diagnosis)	0.254	0.998	0.995	1.001
Gender	0.624	1.093	0.765	1.562
Smokers	0.614	1.015	0.712	1.075
BMI	0.627	1.015	0.954	1.080
Lag time (between onset and diagnosis)	0.330	1.003	0.997	1.008
Hypertension	0.374	1.566	0.583	4.210
Dyslipidaemia	0.941	1.029	0.485	2.184
Number of relapses within the year before diagnosis	0.029	2.340	1.090	5.022
EDSS at the first DMT beginning	0.346	1.099	0.903	1.336
Number of T2-weighted lesions within the year before diagnosis	0.327	1.059	0.839	1.336
Number of T1 Gad+-weighted lesions within the year before diagnosis	0.630	1.377	1.044	1.815
Treatment line	0.062	1.702	0.974	2.973

BMI, Body Mass Index; CI, confidence interval; DMT, disease-modifying therapy; EDSS, Expanded Disability Status Scale; Gad+, Gadolinium.