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. 2021 Feb 20;9(2):180. doi: 10.3390/vaccines9020180

Table 2.

Comparison of the humoral immune response of dogs with hypothyroidism (HypoT) treated with thyroxine and healthy dogs after modified live virus vaccination against canine parvovirus using Bayesian logistic regression.

Total Dogs with HypoT Healthy Dogs p a
total 6 23
pre-vaccination antibody titer
(n b = 29)
<10 0 0/6 (0.0%) 0/23 (0.0%) 1.000
≥10 29 6/6 (100.0%) 23/23 (100.0%)
≥4-fold titer increase
(n = 29)
yes 1 0/6 (0.0%) 1/23 (4.3%) 0.735
no 28 6/6 (100.0%) 22/23 (95.7%)
vaccine-associated adverse events c yes 12 2/6 (33.3%) 10/23 (43.5%) 0.798
no 17 4/6 (66.6%) 13/23 (56.5%)

ap = p-value; b n = number of dogs; c based on owner reports and veterinary examination on days 7 and 28.