Table 1.
Sociodemographic, clinical, and fatigue characteristics for all survivors and for survivors with no, moderate, or severe fatigue separately.
| No. (%) | p Value | Post Hoc | Missing (%) | ||||
|---|---|---|---|---|---|---|---|
| Total (N = 458) |
No Fatigue (n = 134) |
Moderate Fatigue (n = 171) |
Severe Fatigue (n = 133) |
||||
| Age in years | 0.002** | N > M, S | 1.5 | ||||
| M | 49.7 | 52.6 | 47.9 | 48.4 | |||
| SD | 12.3 | 11.7 | 12.0 | 12.9 | |||
| 20−35 years | 71 (16) | 14 (11) | 29 (18) | 27 (21) | 0.005** | ||
| 36−50 years | 147 (32) | 32 (24) | 66 (40) | 42 (32) | |||
| 51−65 years | 186 (41) | 67 (50) | 58 (35) | 52 (40) | |||
| 65−75 years | 47 (10) | 20 (15) | 13 (8) | 11 (8) | |||
| Sex | |||||||
| Female | 231 (50) | 47 (35) | 91 (55) | 85 (64) | <0.001*** | 1.1 | |
| Male | 222 (49) | 87 (65) | 76 (46) | 47 (36) | |||
| BMI (SD) | 0.12 | 2.2 | |||||
| M | 26.1 | 25.3 | 26.5 | 25.9 | |||
| SD | 4.6 | 4.3 | 4.8 | 4.5 | |||
| 16.5−25a | 207 (45) | 73 (56) | 71 (43) | 60 (46) | 0.25 | ||
| 25−30 | 171 (37) | 40 (31) | 67 (40) | 52 (39) | |||
| >30 | 90 (15) | 18 (14) | 28 (17) | 20 (15) | |||
| Living situation | |||||||
| Married | 340 (74) | 107 (80) | 132 (79) | 87 (67) | 0.02* | 1.5 | |
| Educationb | |||||||
| None/Primary education | 7 (2) | 1 (1) | 2 (1) | 4 (3) | 0.70 | 1.5 | |
| High school and vocational education | 229 (50) | 66 (50) | 86 (52) | 65 (50) | |||
| College and university | 215 (47) | 66 (50) | 79 (47) | 62 (47) | |||
| Number of working days | 0.001** | N > S | 1.1 | ||||
| M | 2.9 | 3.4 | 2.9 | 2.5 | |||
| SD | 2.1 | 2.1 | 2.1 | 2.2 | |||
| Employment status | |||||||
| Unemployed | 126 (29) | 28 (21) | 47 (28) | 51 (39) | 0.01 | 1.1 | |
| Employed part-time | 84 (19) | 23 (17) | 37 (22) | 24 (18) | |||
| Employed full-time | 223 (52) | 83 (62) | 83 (50) | 57 (43) | |||
| Diagnosisb | |||||||
| HL | 324 (71) | 92 (70) | 122 (72) | 94 (71) | 0.26 | 1.0 | |
| DLBCL | 74 (16) | 27 (21) | 28 (17) | 17 (13) | |||
| Aggressive NHL | 14 (3) | 1 (1) | 6 (4) | 6 (5) | |||
| Low grade NHL | 8 (2) | 1 (1) | 2 (1) | 5 (4) | |||
| NHL, unknown origin | 26 (6) | 10 (8) | 8 (5) | 7 (5) | |||
| Other | 8 (2) | 1 (1) | 3 (2) | 4 (3) | |||
| Time since diagnosis in years | 0.56 | 2.2 | |||||
| M | 12.0 | 11.6 | 12.5 | 11.3 | |||
| SD | 9.7 | 9.3 | 9.8 | 9.5 | |||
| 0−5 years | 126 (28) | 39 (30) | 44 (27) | 40 (30) | 0.95 | ||
| 6−15 years | 184 (40) | 53 (40) | 68 (41) | 54 (41) | |||
| > 15 years | 138 (30) | 40 (30) | 53 (32) | 38 (29) | |||
| Treatment | |||||||
| Chemotherapy | 424 (93) | 127 (96) | 155 (91) | 122 (92) | 0.32 | 0.4 | |
| Radiotherapy | 276 (60) | 84 (63) | 104 (61) | 76 (57) | 0.59 | 0.4 | |
| Other treatmentsc | 112 (25) | 33 (25) | 39 (23) | 35 (26) | 0.79 | 0.4 | |
| Self-reported comorbidities (in past 12 months) | |||||||
| 0 | 137 (30) | 59 (45) | 43 (26) | 30 (23) | <0.001*** | 2.8 | |
| 1 | 126 (28) | 38 (29) | 51 (31) | 34 (26) | |||
| ≥ 2 | 182 (40) | 35 (27) | 72 (43) | 65 (50) | |||
| Fatigue | |||||||
| General fatigue | <0.001*** | N < M < S | 0 | ||||
| M | 12.7 | 7.9 | 14.0 | 16.3 | |||
| SD | 4.7 | 3.2 | 3.4 | 2.9 | |||
| Cancer-related fatigue (yes) | 300 (66) | 28 (21) | 133 (79) | 127 (96) | <0.001*** | 1.1 | |
Abbreviations: N = no fatigue; M = moderate fatigue; S = severe fatigue; BMI = body mass index; HL = Hodgkin lymphoma; DLBCL = diffuse large B-cell lymphoma; NHL = non-Hodgkin lymphoma.
a.
Two underweight cases (BMI between 16.5 and 18.5) were included in the normal BMI category.
b.
Fisher’s Exact Test reported.
c.
Other treatments include stem cell transplantation, surgery, immunotherapy, or wait and see.
*
p < 0.05. **p < 0.01. ***p < 0.001.