Table 2.

Multivariate Analysis

Clinicopathologic Variables	Hazard Ratio	95% CI	P value
Tumor size (>5.0 cm vs ≤5.0 cm)	0.685	0.136–3.463	0.647
T stage (T3/T4 vs T1/T2)	1.353	0.306–5.971	0.690
TNM stage (Stage III vs Stage I–II)	2.419	1.118–5.233	0.025*
SPRR2B (high vs low)	2.246	1.192–4.230	0.012*

Note: *Indicates P<0.05 by Cox-regression test.