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. 2020 Dec 28;7(1):75–79. doi: 10.1016/j.aace.2020.11.021

Table 2.

Clinical and Biochemical Features of Reported FNAB-Induced PHPT Remission

Authors Age/sex Measurements of parathyroid lesion at diagnosis Measurements of parathyroid lesion at the end of follow-up Calcium/albumin/PTH before FNAB PTH washout levels First measured calcium/PTH after FNAB Calcium/albumin/PTH at the end of follow-up Reoccurrence Length of follow-up (mo) Symptoms after FNAB
Ing and Pelliteri5 74/M 24 × 23 × 26 mm apparently intrathyroidal complex nodule 8 × 9 mm 16.2/NA/341 1800 7.9/NA (2 wk after FNAB) 9.8/NA/83 Yes 16 No
Maxwell et al6 63/F 39 mm intrathyroidal nodule Surgery 12.4/NA/247 10.4/22 (4 d after FNAB) 9.2/NA/71 Yes 1 Neck pain, dysphagia, and voice modification
Kara et al7 67/F 5 × 16 × 29 mm hypoechoic extrathyroidal fusiform nodule Disappeared 11.1a/NA/249 808 9.3/90 (3 mo after FNAB) 9.1∗/NA/53 No 105 Asymptomatic neck swelling
Present case 40/F 24 × 21 × 17 mm apparently intrathyroidal complex nodule 9 × 10 × 13 mm 14.2/3.9/380 181 8.1/NA (6 d after FNAB) 9.4/4.1/30 No 12 No

Abbreviations: F = female; FNAB = fine-needle aspiration biopsy; M = male; NA = not available; PHPT = primary hyperparathyroidism; PTH = parathyroid hormone.

Calcium presented as mg/dL, albumin as g/dL, and PTH as pg/mL.

PTH assays: second-generation for 6 and 7, third-generation for 5 and the present case.

Reference range for PTH: 6-40 pg/mL,5 10-65 pg/mL,6 and 15-88 pg/mL.7

Reference range for serum calcium: 8.3-10.5 mg/dL,5 8.4-10.2 mg/dL,6 and 8.5-10.6 mg/dL.7

a

Corrected calcium using the following formula: corrected calcium (mg/dL) = total serum calcium (mg/dL) + 0.8 × (4 − serum albumin [g/dL]).