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. 2021 Feb 20;22(4):2105. doi: 10.3390/ijms22042105

Table 8.

Characteristics of community living male adults enrolled in the FROST study.

Characteristics Nr of Patients
Men (n,%) 797 (45.2)
Age (years, mean ± SD) 55.75 ± 15.5
Age classes (n,%)
≤50 337 (42.2)
51–70 299 (37.5)
71–90 153 (19.1)
≥91 8 (1.0)
BMI (Kg/m2, mean ± SD) 26.25 ± 3.47
Parental osteoporosis and/or fractures (n,%) 49 (6.1)
Sedentary lifestyle (n,%) 347 (43.5)
Smoking habit (n,%)
Current smokers 178 (22.3)
Former smokers 194 (24.3)
Alcohol intake (n,%)
>4 unit/day 40 (5.0)
Dizziness (n,%) 38 (4.7)
Falls in the previous year (n,%) 17 (2.1)
At least one disease affecting bone metabolism (n,%) * 148 (18.5)
At least one drug affecting bone metabolism (n,%) # 191 (23.9)
At least one fragility fracture (n, %) 27 (3.3)
Diagnosis of osteoporosis (n,%) 9 (1.1)
At least one antifracture treatment (n,%) 13 (1.6)

* The list of diseases affecting bone metabolism includes: diabetes, cancer, COPD, chronic kidney disease (KDIGO stage IV-V), inflammatory bowel diseases, gastrectomy, small bowel resections, malabsorption syndrome, rheumatoid arthritis or major rheumatic diseases, hyperthyroidism, multiple myeloma, celiac disease, primary hyperparathyroidism, hypogonadism. # The list of drugs affecting bone metabolism includes: steroids, aromatase inhibitors or androgen deprivation therapy, antiretroviral therapy, antiepilepctics, warfarin, PPI, thyroid hormones, loop diuretics, heparin, methotrexate, flutaininde, neuroleptics), hypogonadism, malabsorption syndrome.