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. 2021 Feb 20;11(2):355. doi: 10.3390/diagnostics11020355

Table 3.

Association of baseline clinicopathologic characteristics and number of cumulative marker score in the total cohort.

Systemic Inflammatory Markers
Variables 0 (N = 54) 1 (N = 110) 2 (N = 91) 3 (N = 5) p-Value
Age (years), 95%CI 61.0 (59.0–63.5) 63.0 (61.0–64.0) 63.0 (60.0–65.0) 56.0 (46.0–66.0) 0.21
PSA (ng/ml), 95%CI 5.65 (4.97–6.62) 5.68 (5.39–6.08) 5.30 (4.92–5.92) 9.02 (6.09–9.40) 0.04
PSA density (ng/ml/cc), median (95%CI) 0.11 (0.10–0.13) 0.12 (0.10–0.14) 0.12 (0.10–0.13) 0.18 (0.11–0.19) 0.06
Prostate volume (ml), median (95%CI) 50.0 (43.4–52.5) 49.0 (45.0–52.0) 50.0 (45.0–56.0) 52.0 (32.0–60.0) 0.86
ECE, n (%) 11 (20.4) 30 (27.3) 26 (28.6) 4 (80.0) 0.03
Pathological ISUP ≥2, n (%) 8 (14.8) 37 (33.6) 44 (48.3) 5 (100.0) 0.001

95%CI = 95% confidence interval for median; ECE = extracapsular extension; ISUP = International Society of Urological Pathology.