Table 1. Crystal structures of the unliganded form of 3CLpro .
| PDB code | Resolution (Å) | R free (original/re-refined) | Space group† | Temperature | X-ray source | Remarks and references |
|---|---|---|---|---|---|---|
| 6yb7 | 1.25 | 0.192/0.163 | C2_a | Cryo | Synchrotron | — |
| 6m03 | 2.0 | 0.246/0.242 | C2_a | Cryo | Synchrotron | — |
| 6y2e | 1.75 | 0.222/0.221 | C2_a | Cryo | Synchrotron | Zhang et al. (2020 ▸) |
| 6xb0 | 1.8 | 0.201/0.202 | C2_a (I2) | Room | Home | Kneller, Phillips, O’Neill, Tan et al. (2020 ▸) |
| 6m2q | 1.7 | 0.204/0.218 | C2_a | Cryo | Synchrotron | Su et al. (2020 ▸) |
| 6wqf | 2.3 | 0.230/0.239 | C2_a | Cryo | Synchrotron | Kneller, Phillips, O’Neill, Jedrzejczak et al. (2020 ▸) |
| 7jp1 | 1.8 | 0.233/0.248 | C2_a | Cryo | Synchrotron | Lee et al. (2020 ▸) |
| 7bro | 2.0 | 0.259/0.245 | C2_a | Cryo | Synchrotron | Fu et al. (2020 ▸) |
| 7cwb | 1.9 | 0.257/0.282 | C2_a | Room | XFEL | — |
| 7jun | 2.3/2.5 | 0.220 | C2_a | Room | Home/neutron | Kneller, Phillips, Weiss et al. (2020 ▸) |
| 7jvz | 2.5 | 0.217/0.252 | C2_a | Room | XFEL | — |
| 7k3t | 1.2 | 0.187/0.163 | C2_a | Cryo | Synchrotron | — |
| 6y84 | 1.39 | 0.200/0.186 | C2_a | Cryo | Synchrotron | — |
| 7jr3 | 1.55 | 0.183/0.194 | C2_b | Cryo | Synchrotron | — |
| 7jr4 | 1.55 | 0.180/0.186 | C2_b | Cryo | Synchrotron | — |
| 6xkh | 1.28 | 0.175/0.172 | C2_b | Cryo | Synchrotron | — |
| 6xhu | 1.8 | 0.246/0.247 | P21_b | Room | Home | Kneller, Phillips, O’Neill, Tan et al. (2020 ▸) |
| 6wtm | 1.85 | 0.252/0.257 | P21_b | Cryo | Synchrotron | Vuong et al. (2020 ▸) |
| 6xkf | 1.8 | 0.239/0.245 | P21_b | Cryo | Synchrotron | — |
| 7cwc | 2.1 | 0.259/0.255 | P212121 | Room | XFEL | — |
| 7c2y | 1.91 | 0.262/0.233 | P212121 | Cryo | Synchrotron | — |
| 7c2q | 1.93 | 0.265/0.242 | P212121 | Cryo | Synchrotron | — |
| 7jfq | 1.55 | 0.198/0.197 | P212121 | Cryo | Synchrotron | — |
| 6xoa | 2.1 | 0.251/0.278 | P1_c | Cryo | Synchrotron | — |
†
A key to the space-group symbol extended by ‘_k’ is given in Table 3 ▸.