Figure 3.

TAX-treatment attenuates CCl₄-induced oxidative stress. (A) Lipid peroxidation MDA. (B) level of Antioxidant enzyme SOD. (C) GSH activities of mice liver. (D) GSH/GSSG ratios; (E and F) Effects of AFG on expressions of CYP2E1 in liver tissue of mice with liver fibrosis and the CYP2E1 relative fluorescence intensity. Representative immunofluorescence images (green) were taken at 200×, 6-Diamidino-2-phenylindole (DAPI) (Blue) acted as a nuclear counterstain. Data are presented as the mean±SD (n=10). As compared with the normal group, ^#P<0.05 indicates a significant difference, ^##P<0.01 indicates a extremely significant difference; As compared with the model group, *P<0.05 indicates a significant difference, **P<0.01 indicates an extremely significant difference.

Abbreviations: GSH, glutathione; SOD, superoxide dismutase; MDA, malondialdehyde; CYP2E1, cytochrome P450 E1.