Figure 7.

TAX attenuates PI3K/AKT/mTOR signaling pathways in CCl₄-induced liver fibrosis. (A) TAX effects on the countenance of PI3K/AKT/mTOR in the liver tissues of mice were examined by Western blotting examination. (B–D) Densitometric exploration of the p-PI3K/PI3K, p-AKT/AKT, and p-mTOR/TOR. Data presented as the mean±SD (n=10). As compared with the normal group, ^#P<0.05 indicates a significant difference, ^##P<0.01 indicates an extremely significant difference; As compared with the model group, *P<0.05 indicates a significant difference, **P<0.01 indicates an extremely significant difference.

Abbreviations: Akt, protein kinase B; PI3K, phosphatidylinositol 3-kinase; mTOR, mammalian target of rapamycin.