Fig. 2. Localization of SARS-CoV-2 proteins.
A) Heatmap of cell component GO term enrichment of SARS-CoV-2 proteins. B) Western blots of SARS-CoV-2 viral protein-expressing HEK293T cell fractions; whole cell lysate (WCL), cytosol, cytosol/membrane, nucleus/membrane and nucleus fractions. Alpha-tubulin, calnexin, and histone H3 were used as fractionation controls for cytosol, membrane, and nucleus respectively. Schematic C) and table D) depicting the predicted location of all SARS-CoV-2 proteins surveyed in this study based on both the BioID and fractionation analysis.