Fig. 3. COVID disease risk eGenes proximal to viral proteins.

A) Table of GWAS risk SNPs which also scored as BioID hit. B) Map of connectedness of eGenes (Mauve) with BioID interactors (Gray) and the corresponding viral proteins (Purple). eGenes also identified by BioID are outlined in black. GWAS-identified eGenes-associated with antiviral response, cell-cycle, transcription, and translation are also highlighted. C) Virtual 4-C plot showing chromatin contact between TRIM4 promoter and linked COVID disease risk SNP (rs1569055). Genome tracks showing ATAC peaks and contact loops of GM12878, Naïve T, Th-17, and T-reg cells.