Table 1.
1H NMR Data for Compounds 1–5 in DMSO-d6 (500 MHz).
| No. | 1 | 2 | 3 | 4 | 5 |
|---|---|---|---|---|---|
| 2 | 3.09, d (7.0) | 1.41, m (overlap) | 1.50, m | 1.64, m (overlap) | 1.49, m (overlap) |
| 3 | 3.63, d (7.0) | 3.88, m | 3.88, dd (7.2, 1.6) | 3.87, m | 3.88, t (4.4) |
| 5 | 1.26, dd (11.4, 1.7) | 1.41, m (overlap) | 1.66, m | 1.64, m (overlap) | 1.36, m |
| 6α | 1.49, m | 1.56, m | 1.78, m | 5.80, d (11.2) | 1.30, m |
| 6β | 1.37, m | 1.49, m | 1.78, m | 1.49, m (overlap) | |
| 7α | 2.00, m (overlap) | 4.03, m | 1.43, m | 5.39, d (11.2) | 1.81, m (overlap) |
| 7β | 2.00, m (overlap) | 1.43, m | 2.11, dd (14.9, 3.2) | ||
| 8 | 2.38, m | ||||
| 9 | 5.32, br d (7.0) | 5.26, m | 5.57, m | 5.50, br d (8.2) | |
| 10α | 1.59, dd (14.4, 1.2) | 1.87, dd (14.0, 9.1) | 2.43, d (14.4) | 2.18, m | 1.81, m (overlap) |
| 10β | 2.07, dd (14.4, 8.9) | 1.68, m | 2.30, d (14.4) | 2.18, m | 1.99, dd (14.4, 8.9) |
| 11 | 1.66, m | 1.74, m | 1.70, m | 1.64, m (overlap) | 1.69, m |
| 12 | 0.79, d (6.9) | 0.81, d (6.9) | 0.79, d (6.9) | 0.85, d (6.9) | 0.81, d (6.9) |
| 13 | 0.85, d (6.7) | 0.88, d (6.9) | 0.86, d (6.7) | 0.78, d (6.9) | 0.87, d (6.7) |
| 14 | 1.70, s | 1.71, s | 0.96, d (6.9) | 1.74, s | 3.76, s |
| 15 | 0.71, s | 0.88, s | 1.06, s | 0.98, s | 0.92, s |
| 2-OH | 4.16, s | ||||
| 3-OH | 5.39, s | 5.21, d (4.2) | 5.35, s | ||
| 4-OH | 3.53, s | 3.69, s | 3.76, s | 3.60, br s | |
| 7-OH | 4.66, d (5.1) |