Figure 5.

Dual imaging modalities with inorganic nanoparticle-loaded exosomes: (a–d) in vivo imaging of MCF-7 breast tumor-bearing mice after intravenous injection of V₂C QD-loaded exosomes (a,b) PA images and quantified PA intensities of tumor sites at different times, (c,d) _T1-weighted MR images and quantified MR signals of tumor sites 24 h post injection [30]. (e) NIR fluorescence and _T1-weighted images of mouse liver, kidneys, and spleen at 0 h and 24 h post injection of Ag₂Se@Mn QD-labeled exosomes. (f) MR signal quantification in mouse liver, kidneys, and spleen after injection of Ag₂Se@Mn QD-labeled exosomes [31].