Table 2.
Mean difference in pre– to post–PEx treatment ppFEV1, return to ≥90% of baseline ppFEV1, and time to next PEx requiring i.v. antibiotics (IPTW unadjusted and adjusted) in inhaled antibiotic-exposed patients
| IPTW Unadjusted |
IPTW Adjusted |
|||
|---|---|---|---|---|
| Results | P Value | Results | P Value | |
| Change in ppFEV1, estimate (95% CI) | −0.66% (−1.38 to 0.07) | 0.077 | −1.11% (−1.83 to −0.38) | 0.003 |
| Return to ≥90% of baseline ppFEV1, odds ratio (95% CI) | 1.09 (0.96 to 1.24) | 0.16 | 0.94 (0.82 to 1.07) | 0.34 |
| Time to next PEx hazard ratio (95% CI) | 1.01 (0.95 to 1.07) | 0.72 | 1.05 (0.99 to 1.12) | 0.098 |
Definition of abbreviations: CI = confidence interval; IPTW = inverse probability of treatment weighting; i.v. = intravenous; PEx = pulmonary exacerbation; ppFEV1 = percent predicted forced expiratory volume in 1 second.