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. Author manuscript; available in PMC: 2021 Mar 2.
Published in final edited form as: Annu Rev Immunol. 2020 Jan 21;38:341–363. doi: 10.1146/annurev-immunol-100819-121537

Figure 5.

Figure 5

Therapeutic intervention in the HIF pathway. A range of pharmacologic agents with distinct mechanisms of action have been developed to either inhibit or activate the HIF pathway.