Figure 2.

Daily log₁₀ colony-forming units (log₁₀CFU) and log₁₀ time to positivity (log₁₀TTP) for mycobacteria over 7 days for all 59 participants with mutated (black dots) and nonmutated (red crosses) bacteria. The model includes a mutation variable (0, dashed line, or 1, full line): TTP = b₀ + b₁ × CFUs + b₂ × mutations + b₃ × CFUs × mutations. This formula resulted in log₁₀TTP = 2.6324 – 0.0947 × log₁₀CFUs + 0.1133 × mutations – 0.0013 × log₁₀CFUs × mutations; r² = 0.631; P < 0.0001 for b₀, b₁; P = 0.002 for b₂; P = 0.852 for b₃.