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| Miltefosine (30 mg/kg p.o.) | AmBisome (40 mg/kg i.v.) | |||||
|---|---|---|---|---|---|---|
| Parameter | Plasma | Liver | Spleen | Plasma | Liver | Spleen |
| t1/2, h | 63.71 | 63.60 | 71.66 | 3.24 | ND | ND |
| Tmax, hr | 24.00 | 24.00 | 24.00 | 0.05 | 24.00 | 8.00 |
| Cmax, μg/mL | 11.80 | 87.40 | 24.50 | 874.90 | 750.80 | 113.20 |
| AUClast, hr*μg/mL | 640.44 | 4568.79 | 1331.24 | 2853.73 | 16010.44 | 2492.80 |
