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. 2021 Mar 2;15(3):e0009013. doi: 10.1371/journal.pntd.0009013

Table 3. Protein binding of amphotericin B and miltefosine in plasma and tissue.

% bound (mean +/- SD, n = 3)
Dosing Hours post dose Plasma Liver Spleen
AmBisome 40 mg/kg x1 24 99.60 +/- 0.41 99.98 +/- 0.00 99.96 +/- 0.02
Miltefosine 30 mg/kg x1 1 99.92 +/- 0.06 99.97 +/- 0.00 99.93 +/- 0.07
Miltefosine 30 mg/kg x5 1 99.98 +/- 0.00 99.99 +/- 0.00 99.99 +/- 0.00