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. Author manuscript; available in PMC: 2022 Jan 1.
Published in final edited form as: Curr Protoc. 2021 Jan;1(1):e25. doi: 10.1002/cpz1.25

Figure 2. Comparison of the (A) toxic OP and (B) non-OP PON1 status assays using the same population (n = 183).

Figure 2.

Samples were run in triplicate, and each data point corresponds to the average value of the pathlength-corrected triplicate. Activity results are displayed in enzymatic units (U/L for panel 2A and U/mL for panel 2B). The PON1 status carried out in panel A corresponds to the original PON1 status that uses toxic OP substrates (paraoxon and diazoxon) (Furlong et al., 2006; Richter & Furlong, 1999; Richter et al., 2004, 2008, 2009). Panel B displays enzymatic activity results using the non-OP PON1 status described here (Richter et al. 2008 and 2009). In both panels, the open circle data points correspond to individuals homozygous for PON1192Q (QQ), the solid square data points correspond to individuals heterozygous for PON1192QR (QR), and the open triangle data points correspond to individuals homozygous for PON1192R (RR). Reproduced with permission from Richter et al., 2008.